Order Artrotec tablets online in the USA from a licensed pharmacy

Product Name	Artrotec
Dosage	50 mg/200 mcg, 75 mg/200 mcg (diclofenac sodium/misoprostol)
Active Ingredient	Diclofenac sodium + Misoprostol
Form	Delayed‑release oral tablets
Description	For adults with osteoarthritis or rheumatoid arthritis who need NSAID therapy and are at risk of stomach ulcers. Rx only in the USA; carries NSAID boxed warnings and pregnancy contraindication due to misoprostol.
How to Order in the USA	Licensed online pharmacy with telehealth prescription

Artrotec is a U.S. prescription‑only combination tablet that contains diclofenac sodium (a nonsteroidal anti‑inflammatory drug, NSAID) and misoprostol (a prostaglandin E1 analog that helps protect the stomach lining). It is intended for adults who require NSAID therapy to control osteoarthritis (OA) or rheumatoid arthritis (RA) symptoms and who are at high risk of gastric and duodenal ulcers or ulcer complications. By pairing an effective NSAID with a gastroprotective agent in one pill, Artrotec seeks to deliver anti‑inflammatory pain relief while reducing the risk of NSAID‑associated gastrointestinal injury.

In the United States, Artrotec is available through licensed pharmacies and typically requires a valid prescription. Many patients appreciate the convenience of completing a quick online telehealth consultation to obtain a U.S. prescription when appropriate. Our partner pharmacy network supports secure ordering, pharmacist counseling, and discreet home delivery across the USA.

Artrotec price in the USA

Pricing for Artrotec depends on the strength, quantity, manufacturer (brand vs. generic diclofenac/misoprostol), your location, and insurance coverage. In the U.S., many payers prefer the generic equivalent, which can lower out‑of‑pocket costs. Without insurance, typical retail prices per tablet may range from approximately $2 to $8 for generics, though prices vary widely between pharmacies and over time. Brand‑name products may cost more. Bulk quantities often provide better per‑tablet value.

To estimate your cost: check your insurance formulary for coverage and copays, compare pharmacy prices with a coupon or savings card, and consider whether your prescriber can authorize a 90‑day supply for additional savings. Our online pharmacy interface shows current U.S. pricing options during checkout and can apply eligible discounts automatically.

Where can I buy Artrotec in the USA?

Adults in the United States can obtain Artrotec from licensed brick‑and‑mortar pharmacies or through accredited online pharmacies. Because Artrotec is prescription‑only, a valid U.S. prescription is required. If you do not have a current prescription, many customers complete a brief online medical questionnaire reviewed by a U.S.‑licensed clinician. When medically appropriate, a prescription is issued, and your order is dispensed by a licensed pharmacy and shipped to your address.

Our partner pharmacy network emphasizes safety, authenticity, and privacy. Orders are packaged discreetly and shipped using trackable methods. Pharmacists are available to answer questions about dosing, side effects, and interactions before and after purchase.

Prefer to manage everything online? The telehealth + pharmacy model streamlines the process: complete your consultation, the prescriber reviews your case, and once approved, the pharmacy fills the prescription and delivers it to your door anywhere in the USA.

Artrotec USA

Getting Artrotec in the United States is straightforward when you have a valid prescription. If needed, start with a telehealth consultation, choose your preferred tablet strength (50 mg/200 mcg or 75 mg/200 mcg), and select the quantity. Our trusted partner coordinates clinician review, prescription fulfillment, and shipping.

What is Artrotec (diclofenac/misoprostol)?

Artrotec combines two active ingredients:

• Diclofenac sodium: an NSAID that reduces inflammation and relieves pain and swelling in conditions such as OA and RA.
• Misoprostol: a prostaglandin analog that increases protective mucus and bicarbonate secretion in the stomach and helps reduce the risk of gastric and duodenal ulcers caused by NSAIDs.

This fixed‑dose combination is formulated as delayed‑release tablets to help optimize tolerability. It is intended for adult patients who require an NSAID and who are at increased risk for NSAID‑induced ulcers, such as those with a history of ulcer disease, older adults, or patients using concomitant medications that increase GI bleeding risk.

How Artrotec works to manage arthritis pain and protect the stomach

Diclofenac inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis that mediates inflammation, pain, and fever. While this provides symptom relief, NSAID‑related suppression of protective gastric prostaglandins can increase the risk of ulcers and GI bleeding. Misoprostol, a prostaglandin E1 analog, counterbalances that risk by replacing lost mucosal prostaglandins, enhancing mucous and bicarbonate secretion, and supporting mucosal blood flow. Together, they aim to maintain anti‑inflammatory efficacy with additional GI protection in one pill.

Why choose diclofenac + misoprostol instead of an NSAID alone?

For patients who need NSAID therapy and have elevated GI risk, pairing an NSAID with a gastroprotective agent is recommended in U.S. guidelines. Options include combining an NSAID with a proton pump inhibitor (PPI) or using a fixed‑dose NSAID/prostaglandin such as Artrotec. Advantages of Artrotec may include:

• One tablet regimen that delivers both NSAID and GI protection, potentially improving adherence.
• Evidence‑based reduction in the incidence of NSAID‑induced gastric and duodenal ulcers compared with NSAID alone.
• Convenient dosing schedules (commonly twice daily for the 75 mg/200 mcg tablet), depending on your prescriber’s instructions.

However, misoprostol can cause diarrhea and abdominal cramping in some patients, and Artrotec is contraindicated in pregnancy. Your clinician will weigh benefits and risks when selecting the best option for you.

Important safety warnings (boxed warnings)

All systemic NSAIDs, including the diclofenac component of Artrotec, carry U.S. FDA boxed warnings. Key boxed warnings include:

• Cardiovascular risk: NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. Risk may occur early in treatment and may increase with duration of use. Do not use for peri‑operative pain in the setting of coronary artery bypass graft (CABG) surgery.
• Gastrointestinal risk: NSAIDs increase the risk of serious GI adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms, especially in older adults.
• Pregnancy risk (misoprostol): Misoprostol can cause abortion, premature birth, uterine rupture, or birth defects. Artrotec is contraindicated in pregnancy. Women of childbearing potential must not use Artrotec unless they are capable of complying with effective contraception and other precautions outlined by their clinician.

Your healthcare provider will assess your cardiovascular and gastrointestinal risk factors before prescribing Artrotec and will instruct you on necessary precautions.

Who should not take Artrotec?

Do not take Artrotec if you:

• Are pregnant, may be pregnant, or are planning to become pregnant.
• Have a history of hypersensitivity to diclofenac, misoprostol, other prostaglandins, or any tablet component.
• Have experienced asthma, urticaria, or allergic‑type reactions after taking aspirin or other NSAIDs (risk of severe, potentially fatal anaphylaxis).
• Have had recent CABG surgery (used for peri‑operative pain management is contraindicated).

Use with caution and discuss risks with your clinician if you have cardiovascular disease or risk factors, GI ulcer history, liver disease, kidney impairment, dehydration, uncontrolled hypertension, heart failure, inflammatory bowel disease, or if you use anticoagulants or antiplatelet agents.

Use in special populations: pregnancy and breastfeeding

Pregnancy: Artrotec is contraindicated in pregnancy due to misoprostol. Exposure can cause miscarriage, uterine rupture, or serious fetal harm. Women of childbearing potential should not use Artrotec unless they:

• Have a negative pregnancy test within two weeks prior to starting therapy,
• Are able to comply with effective contraception,
• Begin therapy only on the second or third day of the next normal menstrual period (as directed by the prescriber), and
• Have been fully counseled on risks and precautions.

Breastfeeding: Diclofenac appears in breast milk in small amounts; misoprostol is rapidly metabolized to misoprostol acid and very small amounts may be present in breast milk. Discuss with your clinician whether the benefits outweigh potential risks for you and your infant.

Use in older adults and people with other conditions

Older adults are at elevated risk of NSAID‑related GI bleeding, renal effects, and cardiovascular events. Lower effective doses and closer monitoring may be appropriate. Patients with renal or hepatic impairment may require additional monitoring, and Artrotec may be avoided in advanced kidney disease. If you have inflammatory bowel disease, misoprostol‑related diarrhea may exacerbate symptoms—speak with your clinician.

Mechanism of action

Diclofenac inhibits prostaglandin synthesis by blocking COX enzymes, decreasing inflammatory mediators responsible for pain and swelling in joints. Misoprostol acts on gastric parietal cells to reduce acid secretion and on epithelial cells to increase mucous and bicarbonate, preserving mucosal defenses that NSAIDs can otherwise diminish. This dual approach helps maintain GI protection while delivering anti‑inflammatory relief.

Artrotec dosage and administration

Use the lowest effective dose for the shortest duration consistent with treatment goals. Common U.S. dosing patterns include:

• 50 mg/200 mcg tablet: typically taken three to four times daily, as directed.
• 75 mg/200 mcg tablet: typically taken twice daily, as directed.

Always follow your prescriber’s instructions. Take Artrotec with food to improve GI tolerability. Swallow tablets whole—do not crush, chew, or split delayed‑release tablets. If dose adjustments are needed, your clinician will tailor the regimen to your condition and response.

Missed dose and overdose

Missed dose: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not take two doses at once. Resume your regular schedule at the next dose time.

Overdose: Seek emergency medical assistance or contact Poison Control (in the U.S.: 1‑800‑222‑1222) right away. Overdose symptoms may include severe stomach pain, vomiting, drowsiness, dizziness, GI bleeding, dangerously low blood pressure, kidney problems, or breathing difficulties.

Onset of action and what to expect

Many people begin to notice reduced pain and stiffness within hours to a few days of starting Artrotec. Maximum anti‑inflammatory effects may require several days of consistent use. Gastrointestinal side effects, particularly diarrhea or abdominal cramping due to misoprostol, often occur early and may improve after the first week. Let your clinician know if side effects are persistent or severe.

Monitoring and follow-up

Depending on your risk factors and treatment duration, your clinician may recommend periodic assessments such as:

• Blood pressure monitoring.
• Kidney function tests (serum creatinine, BUN), especially in older adults or those with renal risk.
• Liver function tests with longer‑term use of diclofenac.
• Assessment for signs of GI bleeding (black stools, vomiting blood, persistent abdominal pain).

Tell your clinician if you experience chest pain, shortness of breath, weakness on one side of the body, slurred speech, severe headache, or swelling of the legs—these may be signs of serious cardiovascular events.

Pharmacist’s tips for taking Artrotec

Take Artrotec with food and a full glass of water. Avoid alcohol or limit intake, as alcohol increases GI irritation and bleeding risk when combined with NSAIDs. Do not take other NSAIDs (e.g., ibuprofen, naproxen, high‑dose aspirin) unless your prescriber instructs you to. If you need occasional low‑dose aspirin for cardiovascular protection, discuss timing and GI protection strategies with your clinician.

If you’re on anticoagulants (e.g., warfarin), antiplatelets (e.g., clopidogrel), SSRIs/SNRIs, or corticosteroids, ask about additional GI precautions. Report any unusual bruising, bleeding, or black/tarry stools promptly.

Safety precautions and contraindications

Key precautions include:

• Allergy: Avoid Artrotec if you have known hypersensitivity to diclofenac, misoprostol, or other prostaglandins, or if you’ve had asthma/urticaria after aspirin/NSAIDs.
• Cardiovascular: Use cautiously in patients with cardiovascular disease or risk factors. Avoid peri‑CABG use.
• Gastrointestinal: Prior ulcer or GI bleeding increases risk. Consider additional protection and close monitoring.
• Renal/Hepatic: Monitor function in at‑risk patients; avoid in advanced renal disease unless benefits clearly outweigh risks.
• Pregnancy: Contraindicated. Use effective contraception and follow prescriber timing instructions if of childbearing potential.

Possible side effects

Most side effects are mild to moderate, but some can be serious. Contact your clinician if you’re concerned about any symptom.

Common

• Diarrhea, abdominal pain or cramping
• Dyspepsia, nausea, flatulence
• Headache, dizziness
• Edema (swelling), especially in the lower legs

Less common

• Rash, pruritus
• Elevated liver enzymes
• Heartburn, constipation
• Fatigue

Serious (seek medical help immediately)

• Signs of GI bleeding: black or bloody stools, vomiting blood, severe stomach pain
• Allergic reaction: facial/lip/tongue swelling, hives, wheezing, difficulty breathing
• Liver problems: unusual fatigue, right‑upper‑quadrant pain, dark urine, jaundice
• Kidney problems: reduced urination, swelling, sudden weight gain
• Cardiovascular events: chest pain, shortness of breath, weakness on one side, slurred speech
• Severe skin reactions: blistering, peeling, or widespread rash

Reporting side effects

If you experience side effects, contact your prescriber or pharmacist. In the USA, you can also report suspected adverse reactions to the FDA at 1‑800‑FDA‑1088 or via www.fda.gov/medwatch.

Drug interactions

Tell your clinician and pharmacist about all medicines and supplements you use, including OTC products and herbals. Important interactions may include:

• Anticoagulants/antiplatelets (e.g., warfarin, DOACs, clopidogrel): increased bleeding risk.
• SSRIs/SNRIs: additive bleeding risk.
• Other NSAIDs or high‑dose aspirin: increased GI and renal risk.
• ACE inhibitors/ARBs, diuretics: potential effects on kidney function and blood pressure control.
• Lithium: increased lithium levels and toxicity risk.
• Methotrexate: possible increased toxicity.
• Cyclosporine, tacrolimus: increased nephrotoxicity risk.
• Corticosteroids: additive GI risk.
• Alcohol: increases GI irritation and bleeding risk.

This list is not exhaustive. Keep an updated medication list and share it with every healthcare provider.

Storage, handling, and disposal

Store Artrotec at room temperature, away from excess heat and moisture (not in the bathroom). Keep in the original container, tightly closed, and out of reach of children and pets. Do not use after the expiration date on the package. For safe disposal, use a take‑back program if available; otherwise, follow FDA guidance for household disposal. Never share prescription medicines with others.

Cost, insurance, and savings in the USA

Many U.S. insurance plans cover generic diclofenac/misoprostol with a standard copay. Some plans may require prior authorization. If paying cash, pharmacy discount programs and coupons can significantly reduce costs. Ask our support team to check participating pharmacies and savings options in your state. Patients who respond well may benefit from 90‑day supplies to lower per‑tablet costs and minimize refills.

Alternatives and comparisons

Your clinician might consider one of the following alternatives depending on your risk profile and treatment response:

• NSAID + PPI (e.g., diclofenac or naproxen with omeprazole) for GI protection.
• COX‑2 selective NSAID (e.g., celecoxib) ± PPI in high GI risk patients requiring NSAID therapy.
• Topical NSAIDs (e.g., diclofenac gel) for localized OA pain with fewer systemic effects.
• Non‑NSAID analgesics and adjuncts (e.g., acetaminophen, duloxetine, physical therapy) depending on condition and comorbidities.

Artrotec may be preferred when a single tablet regimen that integrates GI protection is desired and tolerated.

Frequently asked questions (FAQs)

Is Artrotec available OTC in the USA? No. Artrotec is prescription‑only in the United States. Many patients use an online telehealth consultation to obtain a prescription when appropriate.

Can I take Artrotec with low‑dose aspirin? Combining with low‑dose aspirin may be medically necessary in some patients, but it increases GI risk. Do not start or stop aspirin without prescriber guidance.

How long can I take Artrotec? Use the lowest effective dose for the shortest duration consistent with your treatment goals. Your clinician will periodically reassess the need for continued NSAID therapy.

Can I drink alcohol while taking Artrotec? It’s best to avoid or limit alcohol because it increases the risk of GI irritation and bleeding with NSAIDs.

What if I develop diarrhea? This is common with misoprostol and often improves after the first week. Stay hydrated. If severe or persistent, contact your clinician—dose adjustments or alternative strategies may be considered.

Is there a generic? Yes. Generic diclofenac sodium/misoprostol is widely available in the USA and may lower costs.

Can I split the tablets? No. Do not crush, split, or chew delayed‑release tablets.

Is Artrotec appropriate if I have kidney or liver issues? Your clinician will evaluate risks. Additional monitoring or alternative therapies may be recommended.

Expert recommendations

For adults who require NSAID therapy for OA or RA and face higher GI risk, Artrotec can be an appropriate option when prescribed and monitored by a clinician. Our U.S.‑licensed partners provide end‑to‑end support—from telehealth evaluation to pharmacist counseling and nationwide delivery. Keep an updated list of all medications, report side effects promptly, and schedule periodic check‑ins to ensure the regimen remains safe and effective for you.

Ready to manage arthritis pain? Order Artrotec today

Get convenient access to Artrotec through our trusted U.S. telehealth and pharmacy partners. Your order is reviewed by a licensed clinician, dispensed by a licensed pharmacy, and delivered discreetly to your door.

• Telehealth prescription available when clinically appropriate
• Fast, secure shipping across the United States
• Authentic medication from licensed U.S. pharmacies
• Competitive pricing and savings options for eligible orders
• Pharmacist support for dosing, side effects, and interactions

Join thousands of patients who rely on licensed online care for timely access to arthritis treatments. Start your order now and take a confident step toward better pain control and GI protection.

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